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| Cat. Number | LY 344864 hydrochloride |
| Chemical Name | LY 344864 hydrochloride |
| CAS Number | [186544-26-3] |
| Mol. Formula | C21H22N3OF.HCl |
| Mol. Weight | 387.88 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[(3R)-3-(Dimethylamino)-2,3,4,9-t etrahydro-1H-carbazol-6-yl]-4-fluorobenzamide hydrochloride |
| Solubility | Soluble to 50 mM in water and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent, selective 5-HT1F receptor agonist (EC50 = 3 nM). Displays > 80-fold selectivity over other 5-HT receptors (Ki values are 0.006, 0.53, 0.55, 0.56, 1.42, 1.70, 3.50, 3.94 and 4.85 μM for 5-HT1F, 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E, 5-HT2B, 5-HT2C, 5-HT2A and 5-HT7 receptors respectively). Inhibits neurogenic dural inflammation in vivo following i.v. and oral administration. Purity: >99 % |
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