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| Cat. Number | LY 2365109 hydrochloride |
| Chemical Name | LY 2365109 hydrochloride |
| CAS Number | [868265-28-5] |
| Mol. Formula | C22H27NO5.HCl |
| Mol. Weight | 421.91 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[2-[4-(1,3-Benzodioxol-5-yl)-2-(1 ,1-dimethylethyl)phenoxy]ethyl]-N-methylglycine hydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Desiccate at RT |
| References | Potent and selective glycine transporter 1 (GlyT1) inhibitor (IC50 values are 15.8 and > 30 000 nM at GlyT1 and GlyT2 respectively). Induces a dose-dependent elevation in CSF levels of glycine, and enhances acetylcholine and dopamine release in the striatum and prefrontal cortex respectively. Produces profound locomotor and respiratory impairments at higher doses. Purity: >98 % |
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