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| Cat. Number | Lestaurtinib |
| Chemical Name | Lestaurtinib |
| CAS Number | [111358-88-4] |
| Mol. Formula | C25H21N3O4 |
| Mol. Weight | 439.46 |
| Qty 1 |
1mg |
| Synonym | (9S,10S,12R)-2,3,9,10,11,12-Hexahyd ro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epo xy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1, 6]benzodiazocin-1-one |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Potent JAK2, FLT3 and TrkA inhibitor (IC50 values are 0.9, 3 and < 25 nM respectively) that prevents STAT5 phosphorylation (IC50 = 20 - 30 nM). Exhibits antiproliferative activity in vitro (IC50 = 30 - 100 nM in HEL92.1.7 cells) and is effective against myeloproliferative disorders in vivo. Purity: >99 % |
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