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| Cat. Number | L-779,450 |
| Chemical Name | L-779,450 |
| CAS Number | [303727-31-3] |
| Mol. Formula | C20H14ClN3O |
| Mol. Weight | 347.8 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-Chloro-5-[2-Phenyl-5-(4-pyridinyl )-1H-imidazol-4-yl]phenol |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Potent, ATP-competitive Raf kinase inhibitor (IC50 = 10 nM) that displays > 7, > 30 and > 70-fold selectivity over p38α, GSK3β and Lck respectively. Suppresses DNA synthesis and induces apoptosis in cells that proliferate in response to Raf-1 and A-Raf but not B-Raf. Purity: >99 % |
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