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| Cat. Number | L 006235 |
| Chemical Name | L 006235 |
| CAS Number | [294623-49-7] |
| Mol. Formula | C24H30N6O2S |
| Mol. Weight | 466.6 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[1-[[(Cyanomethyl)amino]carbonyl] cyclohexyl]-4-[2-(4-methyl-1-piperazinyl)-4-thiazo lyl]benzamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent, reversible cathepsin K inhibitor (IC50 = 0.25 nM) that displays > 4000-fold selectivity over cathepsins B, L and S. Displays reduced selectivity in cell-based assays possibly due to lysosomal accumulation. Reduces collagen breakdown and promotes bone deposition in vivo. Orally active and has intrinsic fluorescence. Purity: >98 % |
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