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/ Products Classification 点击展开+Cat. Number | MPEP hydrochloride |
Chemical Name | MPEP hydrochloride |
CAS Number | [96206-92-7] |
Mol. Formula | C14H11N.HCl |
Mol. Weight | 229.71 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
Solubility | Soluble to 5 mM in water and to 100 mM in DMSO |
Storage condition | Desiccate at +4°C |
References | Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. Also available as part of the Group I mGlu Receptor Tocriset™. Purity: >99 % |