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Cat. Number
MPEP hydrochloride
Chemical Name
MPEP hydrochloride
CAS Number
[96206-92-7]
Mol. Formula
C14H11N.HCl
Mol. Weight
229.71
Qty 1
10mg
Qty 2
50mg
Synonym
2-Methyl-6-(phenylethynyl)pyridine hydrochloride
Solubility
Soluble to 5 mM in water and to 100 mM in DMSO
Storage condition
Desiccate at +4°C
References
Potent and highly selective non-competitive antagonist at the mGlu5 receptor subtype (IC50 = 36 nM) and a positive allosteric modulator at mGlu4 receptors. Centrally active following systemic administration in vivo. Reverses mechanical hyperalgesia in the inflamed rat hind paw. Also available as part of the Group I mGlu Receptor Tocriset™.
Purity: >99 %
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