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Cat. Number
Monastrol
Chemical Name
Monastrol
CAS Number
[254753-54-3]
Mol. Formula
C14H16N2O3S
Mol. Weight
292.35
Qty 1
10mg
Qty 2
50mg
Synonym
1,2,3,4-Tetrahydro-4-(3-hydroxyphen yl)-6-methyl-2-thioxo-5-pyrimidinecarboxylic acid, ethyl ester
Solubility
Soluble to 100 mM in ethanol and to 100 mM in DMSO
Storage condition
Store at RT
References
Potent, cell-permeable, small molecule mitosis inhibitor that does not interact with tubulin. Arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC50 = 14 μM).
Purity: >98 %
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