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| Cat. Number | MK 217 |
| Chemical Name | MK 217 |
| CAS Number | [121268-17-5] |
| Mol. Formula | C4H12NNaO7P2 |
| Mol. Weight | 271.08 |
| Qty 1 |
50mg |
| Synonym | P,P'-(4-Amino-1-hydroxybutylidene)bi s-phosphonic acid monosodium salt |
| Solubility | Soluble to 50 mM in water |
| Storage condition | Desiccate at -20°C |
| References | Osteoclast-mediated bone resorption inhibitor. Binds and blocks farnesyl diphosphate synthase (FPPS) in the HMG-CoA pathway (IC50 = 460 nM for recombinant human FPPS); causes macrophage apoptosis. Inhibits prenylation and sterol biosynthesis in purified osteoclasts. |
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