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| Cat. Number | KN-62 |
| Chemical Name | KN-62 |
| CAS Number | [127191-97-3] |
| Mol. Formula | C38H35N5O6S2 |
| Mol. Weight | 721.84 |
| Qty 1 |
1mg |
| Synonym | 4-[(2S)-2-[(5-isoquinolinylsulfonyl )methylamino]-3-oxo-3-(4-phenyl-1-piperazinyl)prop yl] phenyl isoquinolinesulfonic acid ester |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Desiccate at -20°C |
| References | Selective, cell-permeable inhibitor of CaM kinase II (IC50 = 0.9 μM). Binds directly to the calmodulin binding site of the enzyme. Potent non-competitive antagonist at the P2X7 receptor (IC50 = 15 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™. Purity: >98 % |
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