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| Cat. Number | MG 101 |
| Chemical Name | MG 101 |
| CAS Number | [110044-82-1] |
| Mol. Formula | C20H37N3O4 |
| Mol. Weight | 383.53 |
| Qty 1 |
5mg |
| Synonym | N-Acetyl-L-leucine-L-leucine-L-norl eucinal |
| Solubility | Soluble to 50 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at -20°C |
| References | Calpain inhibitor (IC50 = 0.09 μM) that activates p53-dependent apoptosis in tumor cell lines. Increases activated p53, p21 and caspase levels and promotes cell cycle arrest through inhibition of cyclin D degradation in vitro. Also attenuates ischemia/reperfusion injury in cardiomyocytes, hepatocytes and renal tubular cells through downregulation of iNOS and COX-2 expression. |
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