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Cat. Number
Methotrexate
Chemical Name
Methotrexate
CAS Number
[59-05-2]
Mol. Formula
C20H22N8O5
Mol. Weight
454.44
Qty 1
100mg
Synonym
N-[4-[[(2,4-Diamino-6-pteridinyl)me thyl]methylamino]benzoyl]-L-glutamic acid
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Cytotoxic agent. Inhibits thymidylate synthetase and de novo purine synthesis. Potent folic acid antagonist; inhibits dihydrofolate reductase. Also inhibits Ras carboxyl methylation in DKOB8 cells, leading to decreased p44 and Akt activation.
Purity: >99 %
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