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/ Products Classification 点击展开+Cat. Number | Methotrexate |
Chemical Name | Methotrexate |
CAS Number | [59-05-2] |
Mol. Formula | C20H22N8O5 |
Mol. Weight | 454.44 |
Qty 1 |
100mg |
Synonym | N-[4-[[(2,4-Diamino-6-pteridinyl)me thyl]methylamino]benzoyl]-L-glutamic acid |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at RT |
References | Cytotoxic agent. Inhibits thymidylate synthetase and de novo purine synthesis. Potent folic acid antagonist; inhibits dihydrofolate reductase. Also inhibits Ras carboxyl methylation in DKOB8 cells, leading to decreased p44 and Akt activation. Purity: >99 % |