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| Cat. Number | 3-MATIDA |
| Chemical Name | 3-MATIDA |
| CAS Number | [518357-51-2] |
| Mol. Formula | C8H9NO4S |
| Mol. Weight | 215.23 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | α-Amino-5-carboxy-3-methyl-2-thiophe neacetic acid |
| Solubility | Soluble to 100 mM in 1eq. NaOH and to 50 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent metabotropic glutamate mGlu1 receptor antagonist (IC50 = 6.3 μM at rat mGlu1a). Displays ≥ 40-fold selectivity over other receptors: mGlu5, mGlu2, mGlu4a (IC50 > 300 μM), NMDA and AMPA (IC50 = 250 μM). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro. Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo. Purity: >99 % |
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