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/ Products Classification 点击展开+Cat. Number | M40 |
Chemical Name | M40 |
CAS Number | [143896-17-7] |
Mol. Formula | C94H145N23O24 |
Mol. Weight | 1981.33 |
Qty 1 |
1mg |
Storage condition | Desiccate at -20°C |
References | Potent, non-selective galanin receptor antagonist (Ki values are 1.82 and 5.1 nM at GAL1 and GAL2 respectively) that inhibits galanin (1-29) (Cat. No. 2696) binding in rat brain in vitro (IC50 = 3 - 15 nM). Attenuates the antidepressant effects of fluoxetine (Cat. No. 0927) and blocks galanin-induced food intake in vivo. Also exhibits weak partial agonist activity at peripheral GAL2 receptors at doses > 100 nM. |