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| Cat. Number | NVP DPP 728 dihydrochloride |
| Chemical Name | NVP DPP 728 dihydrochloride |
| CAS Number | [247016-69-9] |
| Mol. Formula | C15H18N6O.2HCl |
| Mol. Weight | 371.27 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-[[2-[[2-(2S)-2-Cyano-1-pyrrolidin yl]-2-oxoethyl]amino]ethyl]amino-3-pyridinecarbono nitrile dihydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | Potent, orally active dipeptidyl peptidase (DPP)-IV inhibitor (Ki = 11 nM, IC50 = 14 nM) that displays > 15 000-fold selectivity over DPP-II and a range of proline-cleaving proteases. Exhibits antidiabetic activity in vivo; improves glucose tolerance, increases glucagon-like peptide 1 (GLP-1) and insulin levels, augments insulin secretion and GLUT-2 levels, and reduces (preserves) islet size. Purity: >98 % |
下一个：187-1, N-WASP inhibitor上一个：NVP 231 |
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