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/ Products Classification 点击展开+Cat. Number | NSC 23766 |
Chemical Name | NSC 23766 |
CAS Number | [733767-34-5] |
Mol. Formula | C24H35N7.3HCl |
Mol. Weight | 530.97 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N6-[2-[[4-(Diethylamino)-1-methylbu tyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-qu inolinediamine trihydrochloride |
Solubility | Soluble to 100 mM in water |
Storage condition | Desiccate at RT |
References | Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells. Purity: >99 % |
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