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Cat. Number
NSC 23766
Chemical Name
NSC 23766
CAS Number
[733767-34-5]
Mol. Formula
C24H35N7.3HCl
Mol. Weight
530.97
Qty 1
10mg
Qty 2
50mg
Synonym
N6-[2-[[4-(Diethylamino)-1-methylbu tyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-4,6-qu inolinediamine trihydrochloride
Solubility
Soluble to 100 mM in water
Storage condition
Desiccate at RT
References
Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC50 ~ 50 μM) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and is reported to reverse tumor cell phenotyes in prostate cancer cells.
Purity: >99 %
下一个:NSC 3852上一个:NSC 146109 hydrochloride
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