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| Cat. Number | NSC 109555 ditosylate |
| Chemical Name | NSC 109555 ditosylate |
| CAS Number | [15427-93-7] |
| Mol. Formula | C19H24N10O.2C7H8O3S |
| Mol. Weight | 752.86 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4,4'-diacetyldiphenylurea bis(guanylhydrazone) ditosylate |
| Solubility | Soluble to 10 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Selective, reversible, ATP-competitive Chk2 inhibitor (IC50 = 0.2 μM) that displays no effect on a range of other kinases including Chk1 (IC50 > 10 μM). Inhibits histone H1 phosphorylation (IC50 = 0.24 μM) and attenuates mitochondrial ATP synthesis. Exhibits antiproliferative activity in a number of leukemias in vivo. Purity: >98 % |
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