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| Cat. Number | NPS 2143 hydrochloride |
| Chemical Name | NPS 2143 hydrochloride |
| CAS Number | [284035-33-2] |
| Mol. Formula | C24H25ClNO2.HCl |
| Mol. Weight | 445.38 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-Chloro-6-[(2R)-3-[[1,1-dimethyl-2 -(2-naphthalenyl)ethyl]amino-2-hydroxypropoxy]benz onitrile hydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Desiccate at RT |
| References | Selective Ca2+-sensing receptor antagonist. Blocks increases in cytoplasmic Ca2+ concentrations elicited by human Ca2+ receptors expressed in HEK293 cells (IC50 = 43 nM). Also stimulates parathyroid hormone secretion from bovine parathyroid cells (EC50 = 41 nM). Orally active calcilytic compound. Purity: >99 % |




