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| Cat. Number | Nicorandil |
| Chemical Name | Nicorandil |
| CAS Number | [65141-46-0] |
| Mol. Formula | C8H9N3O4 |
| Mol. Weight | 211.18 |
| Qty 1 |
50mg |
| Synonym | N-[2-(Nitrooxy)ethyl]-3-pyridinecar boxamide |
| Solubility | Soluble to 20 mM in water |
| Storage condition | Desiccate at +4°C |
| References | KATP channel opener and NO donor, clinically used as antianginal agent. Preferentially activates SUR2B- versus SUR2A-containing KATP channels (EC50 values are 10 and > 500 mM respectively) and causes 1.6-fold increase in cardiac eNOS expression. Displays coronary and peripheral vasodilatory properties, reduces both pre- and after-load, and increases coronary blood flow. Also displays cardioprotective effects, possibly through ischemic preconditioning. |
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