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Cat. Number
NGB 2904
Chemical Name
NGB 2904
CAS Number
[189060-98-8]
Mol. Formula
C28H29Cl2N3O.HCl
Mol. Weight
530.92
Qty 1
10mg
Qty 2
50mg
Synonym
N-[4-[4-(2,3-Dichlorophenyl)-1-pipe razinyl]butyl]-9H-fluorene-2-carboxamide
Solubility
Soluble to 25 mM in DMSO and to 5 mM in ethanol
Storage condition
Desiccate at +4°C
References
Potent and selective dopamine D3 receptor antagonist (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). Potently antagonizes quinpirole-stimulated mitogenesis (IC50 = 6.8 nM). Attenuates cocaine's rewarding effects and inhibits relapse to drug-seeking behavior.
Purity: >98 %
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