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| Cat. Number | Necrostatin-1 |
| Chemical Name | Necrostatin-1 |
| CAS Number | [4311-88-0] |
| Mol. Formula | C13H13N3OS |
| Mol. Weight | 259.33 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 5-(1H-Indol-3-ylmethyl)-3-methyl-2- thioxo-4-imidazolidinone |
| Solubility | Soluble to 30 mM in DMSO and to 15 mM in ethanol |
| Storage condition | Store at RT |
| References | ATP-competitive death domain receptor-associated adaptor kinase (RIP1) allosteric inhibitor (EC50 = 182 nM). Blocks non-apoptotic cell death via inhibition of a specific cellular pathway, necroptosis, which leads to necrosis (EC50 = 494 nM). Reduces ischemic brain injury in a mouse model of stroke. Purity: >99 % |
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