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/ Products Classification 点击展开+Cat. Number | Nebivolol hydrochloride |
Chemical Name | Nebivolol hydrochloride |
CAS Number | [152520-56-4] |
Mol. Formula | C22H25F2NO4.HCl |
Mol. Weight | 441.9 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (±)-[2R*(1S*5S*(S*))]-α,α'-[Iminobis(me thylene)bis(6-fluoro-3,4-dihydro-2H-1-benzopyran-2 -methanol) |
Solubility | Soluble to 100 mM in DMSO and to 10 mM in ethanol |
Storage condition | Desiccate at RT |
References | Highly selective β1-adrenoceptor antagonist (Ki values are 0.88, 20, 44, 700, 1160, 2400 and 4000 nM at β1, 5-HT1A, β2, 5-HT2, α1, H1 and D2 receptors respectively). Induces vasodilation via a nitric oxide- and cGMP-dependent mechanism (EC50 = 11.36 μM in renal arteries) and displays antihypertensive activity in vivo. Purity: >98 % |
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