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Cat. Number
Narciclasine
Chemical Name
Narciclasine
CAS Number
[29477-83-6]
Mol. Formula
C14H13NO7
Mol. Weight
307.26
Qty 1
1mg
Synonym
(2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro- 2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthri din-6(2H)-one
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at -20°C
References
Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC50 = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization.
Purity: >98 %
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