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/ Products Classification 点击展开+Cat. Number | Narciclasine |
Chemical Name | Narciclasine |
CAS Number | [29477-83-6] |
Mol. Formula | C14H13NO7 |
Mol. Weight | 307.26 |
Qty 1 |
1mg |
Synonym | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro- 2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthri din-6(2H)-one |
Solubility | Soluble to 100 mM in DMSO |
Storage condition | Store at -20°C |
References | Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC50 = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization. Purity: >98 % |
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