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| Cat. Number | Narciclasine |
| Chemical Name | Narciclasine |
| CAS Number | [29477-83-6] |
| Mol. Formula | C14H13NO7 |
| Mol. Weight | 307.26 |
| Qty 1 |
1mg |
| Synonym | (2S,3R,4S,4aR)-3,4,4a,5-Tetrahydro- 2,3,4,7-tetrahydroxy-(1,3)dioxolo(4,5-j)phenanthri din-6(2H)-one |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Exhibits antiproliferative and pro-apoptotic effects in carcinoma cells and displays cytotoxic activity against a panel of 60 cancer cell lines (mean IC50 = 47 nM). Activity decreases rate of cell division and increases mitosis duration in vitro. Also modulates the Rho/ROCK/LIM kinase/cofilin pathway; stimulates RhoA activation and induces actin polymerization. Purity: >98 % |
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