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| Cat. Number | ONO 4817 |
| Chemical Name | ONO 4817 |
| CAS Number | [223472-31-9] |
| Mol. Formula | C22H28N2O6 |
| Mol. Weight | 416.47 |
| Qty 1 |
10mg |
| Synonym | N-[(1S,3S)-1-[(Ethoxymethoxy)methyl ]-4-(hydroxyamino)-3-methyl-4-oxobutyl]-4-phenoxyb enzamide |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at RT |
| References | Broad spectrum MMP inhibitor; Ki values are 0.45, 0.73, 1.1, 1.1, 2.1, 42 and 2500 nM for MMP-12, MMP-2, MMP-8, MMP-13, MMP-9, MMP-3 and MMP-7 respectively and IC50 = 1600 nM for MMP-1). Displays no activity at other proteases up to a concentration of 100 μM. Exhibits antiangiogenic and anti-invasive properties on lung metastasis of murine renal cell carcinoma. Purity: >99 % |
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