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| Cat. Number | PSC 833 |
| Chemical Name | PSC 833 |
| CAS Number | [121584-18-7] |
| Mol. Formula | C63H111N11O12 |
| Mol. Weight | 1214.62 |
| Qty 1 |
1mg |
| Synonym | 6-[(2S,4R,6E)-4-methyl-2-(methylami no)-3-oxo-6-octenoic acid]-7-L-valine-cyclosporin A |
| Solubility | Soluble to 4 mM in DMSO |
| Storage condition | Store at -20°C |
| References | P-glycoprotein (P-gp) modulator; inhibits P-gp-mediated multidrug-resistance (MDR). Reverses resistance to several cytotoxic drugs including mitoxantrone and doxorubicin (resistance factors are 2.0 and 6.5 respectively) in human MDR cancer cell lines. Non-immunosuppressive analog of cyclosporin A (Cat. No. 1101). Purity: >98 % |
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