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Cat. Number
Prion Protein 106-126 (human)
Chemical Name
Prion Protein 106-126 (human)
CAS Number
[148439-49-0]
Mol. Formula
C80H138N26O24S2
Mol. Weight
1912.26
Qty 1
1mg
Storage condition
Desiccate at -20°C
References
Prion peptide fragment that shares many physiochemical features with PrPSc. Exhibits neurotoxicity caused by amplification of PrPC-associated signaling responses and induces NF-κB-mediated apoptosis in the mouse neuroblastoma cell line N2a. Forms β-sheet-rich, insoluble, protease-resistant fibrils and is used as a model to study prion diseases in vitro.
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