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| Cat. Number | PP 121 |
| Chemical Name | PP 121 |
| CAS Number | [1092788-83-4] |
| Mol. Formula | C17H17N7 |
| Mol. Weight | 319.36 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-Cyclopentyl-3-(1H-pyrrolo[2,3-b]p yridin-5-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | Soluble to 100 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Dual inhibitor of receptor tyrosine kinases (RTKs) (IC50 < 0.02 μM for Abl, Src, VEGFR-2 and PDGFR) and PI 3-K family kinases (IC50 < 0.06 μM for p110α, DNA-PK and mTOR). Exhibits no significant effect on receptor serine/threonine kinases (RSTKs). Blocks the proliferation of tumor cells by direct inhibition of PI 3-K, mTOR, Src and the VEGF receptor. Purity: >99 % |
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