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| Cat. Number | PP 1 |
| Chemical Name | PP 1 |
| CAS Number | [172889-26-8] |
| Mol. Formula | C16H19N5 |
| Mol. Weight | 281.36 |
| Qty 1 |
10mg |
| Synonym | 1-(1,1-Dimethylethyl)-1-(4-methylph enyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Solubility | Soluble to 10 mM in DMSO and to 10 mM in ethanol |
| Storage condition | Desiccate at +4°C |
| References |
Potent inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also moderately inhibits p38, CSK, PDGF receptors, RET-derived oncoproteins, c-Kit and Bcr-Abl. |
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