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/ Products Classification 点击展开+Cat. Number | PNU 37883 hydrochloride |
Chemical Name | PNU 37883 hydrochloride |
CAS Number | [57568-80-6] |
Mol. Formula | C21H35N3O.HCl |
Mol. Weight | 381.98 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | N-Cyclohexyl-N'-tricyclo[3.3.1.13,7] dec-1-yl-4-morpholinecarboximidamide hydrochloride |
Solubility | Soluble to 25 mM in DMSO and to 100 mM in ethanol |
Storage condition | Desiccate at RT |
References | Novel antagonist selective for the vascular form of KATP channel; inhibits KATP currents in isolated mesenteric artery smooth muscle cells (Kd = 65 nM) but not in cardiac or skeletal myocytes. Inhibits blood vessel relaxation and hypotension induced by pinacidil in vivo. Displays weak diuretic effects. Purity: >99 % |
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