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| Cat. Number | PI 103 hydrochloride |
| Chemical Name | PI 103 hydrochloride |
| CAS Number | [371935-74-9] |
| Mol. Formula | C19H16N4O3.HCl |
| Mol. Weight | 384.82 |
| Qty 1 |
1mg |
| Qty 2 | 50mg |
| Synonym | 3-[4-(4-Morpholinylpyrido[3',2':4,5]f uro[3,2-d]pyrimidin-2-yl]phenol hydrochloride |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Inhibitor of DNA-PK, PI 3-kinase (p110α) and mTOR (IC50 values are 2, 8, 20, 26, 48, 83, 88, 150, 850, 920, ~ 1000 and 2300 nM for DNA-PK, p110α, mTORC1, PI3KC2β, p110δ, mTORC2, p110β, p110γ, ATR, ATM, PI3KC2α and hsVPS34 respectively). Inhibits growth of human tumor xenografts in mice in vivo. Purity: >98 % |
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