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| Cat. Number | PG 01 |
| Chemical Name | PG 01 |
| CAS Number | [853138-65-5] |
| Mol. Formula | C28H29N3O2 |
| Mol. Weight | 439.55 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-Methyl-N-[2-[[4-(1-Methylethyl)ph enyl]amino]-2-1H-indole-3-acetamide |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. Corrects gating defects of CFTR mutants such as ΔF508 (Ka = 0.3 μM), E193K and G970R (Kd values are 0.22 μM and 0.45 μM respectively). Increases ΔF508-CFTR Cl- currents in the presence of forskolin; displays no effect on Ca2+-activated Cl- current. Purity: >98 % |




