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| Cat. Number | PF 4708671 |
| Chemical Name | PF 4708671 |
| Mol. Formula | C19H21F3N6 |
| Mol. Weight | 390.41 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 2-[[4-(5-Ethylpyrimidin-4-yl)pipera zin-1-yl]methyl]-5-(trifluoromethyl)-1H-benzo[d]im idazole |
| Solubility | Soluble to 75 mM in DMSO and to 50 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) (Ki = 20 nM; IC50 = 160 nM). Suppresses the S6K1-mediated phosphorylation of S6, Rictor and mTOR in response to IGF1; displays no effect on the activity of RSK and MSK in vivo. Exhibits no significant inhibition of S6K2 or other AGC kinases (e.g. Akt, PKA and ROCK) in vitro. Purity: >97 % |
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