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| Cat. Number | PAC 1 |
| Chemical Name | PAC 1 |
| CAS Number | [315183-21-2] |
| Mol. Formula | C23H28N4O2 |
| Mol. Weight | 392.5 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 4-(Phenylmethyl)-1-piperazineacetic acid [[2-hydroxy-3-(2-propenyl)phenyl]methylene]hydrazi de |
| Solubility | Soluble to 75 mM in 1eq. HCl and to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Procaspase-activating compound; activates procaspase-3 to produce caspase-3 (EC50 = 0.22 μM). Also activates procaspase-7 in a less efficient manner (EC50 = 4.5 μM). Pro-apoptotic; induces apoptosis in both cancerous and non-cancerous cells dependent on procaspase-3 concentration (IC50 values are 0.003 - 1.41 and 5.02 - 9.98 μM respectively). Purity: >98 % |
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