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| Cat. Number | SB 239063 |
| Chemical Name | SB 239063 |
| CAS Number | [193551-21-2] |
| Mol. Formula | C20H21FN4O2 |
| Mol. Weight | 368.41 |
| Qty 1 |
10mg |
| Synonym | trans-4-[4-(4-Fluorophenyl)-5-(2-me thoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol |
| Solubility | Soluble to 10 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | Potent and selective p38 MAP kinase inhibitor (IC50 = 44 nM for p38α). Displays > 220-fold selectivity over ERK, JNK1 and other kinases; ~ 3-fold more selective than SB 203580 (Cat. Nos. 1202 and 1402). Reduces inflammatory cytokine production and is neuroprotective following oral administration in vivo. Purity: >98 % |
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