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| Cat. Number | RS 504393 |
| Chemical Name | RS 504393 |
| CAS Number | [300816-15-3] |
| Mol. Formula | C25H27N3O3 |
| Mol. Weight | 417.5 |
| Qty 1 |
10mg |
| Synonym | 6-Methyl-1'-[2-(5-methyl-2-phenyl-4- oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piper idin]-2(1H)-one |
| Solubility | Soluble to 10 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Extremely selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Inhibits MCP-1 chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys. Purity: >99 % |
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