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| Cat. Number | RS 102895 hydrochloride |
| Chemical Name | RS 102895 hydrochloride |
| CAS Number | [300815-41-2] |
| Mol. Formula | C21H21F3N2O2.HCl |
| Mol. Weight | 426.86 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1'-[2-[4-(Trifluoromethyl)phenyl]eth yl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)- one hydrochloride |
| Solubility | Soluble to 75 mM in DMSO |
| Storage condition | Desiccate at RT |
| References | CCR2-selective chemokine receptor antagonist (IC50 values are 0.36 and 17.8 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Blocks MCP-1-stimulated calcium influx and chemotaxis with IC50 values of 32 nM and 1.7 μM respectively. Also inhibits α1A, α1D and 5-HT1A receptors. Purity: >99 % |
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