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Cat. Number
RO-3
Chemical Name
RO-3
Mol. Formula
C16H22N4O2
Mol. Weight
302.37
Qty 1
10mg
Synonym
5-[[4,5-Dimethoxy-2-(methylethyl)ph enyl]methyl]-2,4-pyrimidinediamine
Solubility
Soluble to 100 mM in DMSO
Storage condition
Store at RT
References
Selective homomeric P2X3 and heteromeric P2X2/3 receptor antagonist (pIC50 values are 7.0 and 5.9 respectively) that exhibits no activity at P2X1, P2X2, P2X4, P2X5 and P2X7 receptors (IC50 > 10 μM). Attenuates nociceptive sensitivity in animal models of pain. Orally active and brain penetrant.
Purity: >98 %
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