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Cat. Number
Ro 61-8048
Chemical Name
Ro 61-8048
CAS Number
[199666-03-0]
Mol. Formula
C17H15N3O6S2
Mol. Weight
421.45
Qty 1
10mg
Qty 2
50mg
Synonym
3,4-Dimethoxy-N-[4-(3-nitrophenyl)- 2-thiazolyl]benzenesulfonamide
Solubility
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Storage condition
Store at +4°C
References
Potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM). Increases kynurenic acid levels to concentrations that antagonize the glycine site of NMDA receptors. Brain penetrant and exhibits antidystonic, anticonvulsant and neuroprotective activities.
Purity: >99 %
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