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| Cat. Number | Ro 31-8220 mesylate |
| Chemical Name | Ro 31-8220 mesylate |
| CAS Number | [125314-64-9] |
| Mol. Formula | C25H23N5O2S.CH3SO3H |
| Mol. Weight | 553.65 |
| Qty 1 |
10mg |
| Synonym | 3-[3-[2,5-Dihydro-4-(1-methyl-1H-in dol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl]-1H-indol-1-yl] propyl carbamimidothioic acid ester mesylate |
| Solubility | Soluble to 100 mM in DMSO and to 5 mM in ethanol |
| Storage condition | Desiccate at -20°C |
| References | Protein kinase C inhibitor, with activity at other protein kinases (IC50 values are 33, 3, 8, 15 and 38 nM for PKCα, MAPKAP-K1b, MSK1, GSK3β and S6K1 respectively). Activates JNK and glycogen synthase, and inhibits MAPK and ERK2, in rat adipocytes and L6 myotubes. Also inhibits voltage-dependent Na+ channels in the micromolar range. Purity: >97 % |
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