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| Cat. Number | RN 1747 |
| Chemical Name | RN 1747 |
| CAS Number | [102448-59-6] |
| Mol. Formula | C17H18CIN3O4S |
| Mol. Weight | 395.87 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-(4-Chloro-2-nitrophenyl)sulfonyl- 4-benzylpiperazine |
| Solubility | Soluble to 100 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Selective TRPV4 agonist (EC50 values are 0.77, 4.0 and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively). Displays selectivity over other TRP channels (EC50 values are 0.77, >30, >30 and >100 μM for TRPV4, TRPM8, TRPV3 and TRPV1 receptors respectively). Also antagonizes TRPM8 at relevant concentrations (IC50 = 4 μM). |
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