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| Cat. Number | RITA |
| Chemical Name | RITA |
| CAS Number | [213261-59-7] |
| Mol. Formula | C14H12O3S2 |
| Mol. Weight | 292.37 |
| Qty 1 |
1mg |
| Qty 2 | 10mg |
| Synonym | 5,5'-(2,5-Furandiyl)bis-2-thiophenem ethanol |
| Solubility | Soluble to 100 mM in DMSO and to 25 mM in ethanol |
| Storage condition | Store at -20°C |
| References | Anti-tumor agent that binds wild-type p53 (Kd = 1.5 nM) preventing p53-MDM2 (HDM2) interaction. Induces p53 accumulation and stimulates apoptosis in tumor cell lines expressing wild-type p53 in vitro and in vivo. Inhibits HPV-E6-mediated proteasomal degradation. Suppresses expression of cervical carcinoma HeLa xenografts in vivo. Purity: >97 % |
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