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| Cat. Number | Reversan |
| Chemical Name | Reversan |
| CAS Number | [313397-13-6] |
| Mol. Formula | C26H27N5O2 |
| Mol. Weight | 441.52 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[3-(4-Morpholinyl)propyl]-5,7-dip henylpyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Solubility | Soluble to 25 mM in DMSO |
| Storage condition | Store at RT |
| References | Selective inhibitor of multidrug resistance-associated protein 1 (MRP1) and P-glycoprotein (P-gp). Increases the sensitivity of MRP1-overexpressing tumor cells (MCF7/VP) to doxorubicin (Cat. No. 2252), vincristine (Cat. No. 1257) and etoposide (Cat. No. 1226) by 3.8-, 14.6- and 11.6-fold respectively. Increases the efficacy of vincristine and etoposide in murine models of neuroblastoma in vivo. Displays at activity on MRP2, MRP3, MRP5 and MRP5 transporters. Purity: >99 % |
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