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| Cat. Number | Sunitinib malate |
| Chemical Name | Sunitinib malate |
| CAS Number | [341031-54-7] |
| Mol. Formula | C22H27FN4O2.C4H2O5 |
| Mol. Weight | 532.56 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[2-(Diethylamino)ethyl]-5-[(Z)-(5 -fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidine)methy l]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioate salt |
| Solubility | Soluble to 25 mM in DMSO |
| Storage condition | Store at +4°C |
| References | Potent, ATP-competitive VEGFR, PDGFRβ and KIT inhibitor (Ki values are 2, 9, 17, 8 and 4 nM for VEGFR -1, -2, -3, PDGFRβ and KIT respectively). Also inhibits cellular receptor phosphorylation of FLT3, RET and CSF-1R. Exhibits antiangiogenic and antitumor activity in multiple xenograft models. Purity: >99 % |
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