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/ Products Classification 点击展开+Cat. Number | Stattic |
Chemical Name | Stattic |
CAS Number | [19983-44-9] |
Mol. Formula | C8H5NO4S |
Mol. Weight | 211.19 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 6-Nitrobenzo[b]thiophene 1,1-dioxide |
Solubility | Soluble to 50 mM in DMSO and to 5 mM in ethanol |
Storage condition | Store at +4°C |
References | Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines. Purity: >99 % |