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Cat. Number
Stattic
Chemical Name
Stattic
CAS Number
[19983-44-9]
Mol. Formula
C8H5NO4S
Mol. Weight
211.19
Qty 1
10mg
Qty 2
50mg
Synonym
6-Nitrobenzo[b]thiophene 1,1-dioxide
Solubility
Soluble to 50 mM in DMSO and to 5 mM in ethanol
Storage condition
Store at +4°C
References
Small molecule inhibitor of STAT3. Inhibits binding of tyrosine-phosphorylated peptide motifs to STAT3 SH2 domain and inhibits STAT3 activation, dimerization and nuclear translocation. Displays selectivity over STAT1, STAT5, c-Myc/Max, Jun/Jun and Lck. Induces apoptosis in STAT3-dependent cancer cell lines.
Purity: >99 %
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