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| Cat. Number | SSR 146977 hydrochloride |
| Chemical Name | SSR 146977 hydrochloride |
| CAS Number | [264618-44-2] |
| Mol. Formula | C35H42Cl2N4O2.HCl |
| Mol. Weight | 658.11 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N1-[1-3-[(3R)-1-Benzoyl-3-(3-(3,4-d ichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-pipe ridinyl]-N,N-dimethylurea hydrochloride |
| Solubility | Soluble to 100 mM in DMSO and to 100 mM in ethanol |
| Storage condition | Store at +4°C |
| References | Potent and selective NK3 receptor antagonist (Ki values are 0.26 and 19.3 nM in CHO cells expressing the human NK3 and NK2 receptor respectively). Also inhibits senktide (Cat. No. 1068) -induced inositol monophosphate formation and intracellular calcium mobilization (IC50 = 10 nM). Purity: >98 % |
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