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Cat. Number
SR 49059
Chemical Name
SR 49059
CAS Number
[150375-75-0]
Mol. Formula
C28H27Cl2N3O7S
Mol. Weight
620.5
Qty 1
10mg
Synonym
(2S)-1-[[(2R,3S)-5-Chloro-3-(2-chlo rophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-di hydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolid inecarboxamide
Solubility
Soluble to 30 mM in DMSO
Storage condition
Store at +4°C
References
Potent and selective non-peptide vasopressin V1A receptor antagonist; devoid of agonist activity. Displays high affinity and efficacy at both rat (Ki = 1.6 nM) and human (Ki = 1.1 - 6.3 nM) V1A receptors. Potently antagonizes arginine vasopressin-induced effects in vitro (IC50 = 3.7 nM for inhibition of human platelet aggregation) and is orally active in vivo.
Purity: >99 %
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