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/ Products Classification 点击展开+Cat. Number | SR 49059 |
Chemical Name | SR 49059 |
CAS Number | [150375-75-0] |
Mol. Formula | C28H27Cl2N3O7S |
Mol. Weight | 620.5 |
Qty 1 |
10mg |
Synonym | (2S)-1-[[(2R,3S)-5-Chloro-3-(2-chlo rophenyl)-1-[(3,4-dimethoxyphenyl)sulfonyl]-2,3-di hydro-3-hydroxy-1H-indol-2-yl]carbonyl]-2-pyrrolid inecarboxamide |
Solubility | Soluble to 30 mM in DMSO |
Storage condition | Store at +4°C |
References | Potent and selective non-peptide vasopressin V1A receptor antagonist; devoid of agonist activity. Displays high affinity and efficacy at both rat (Ki = 1.6 nM) and human (Ki = 1.1 - 6.3 nM) V1A receptors. Potently antagonizes arginine vasopressin-induced effects in vitro (IC50 = 3.7 nM for inhibition of human platelet aggregation) and is orally active in vivo. Purity: >99 % |