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/ Products Classification 点击展开+Cat. Number | SR 202 |
Chemical Name | SR 202 |
CAS Number | [76541-72-5] |
Mol. Formula | C11H17ClO7P2 |
Mol. Weight | 358.65 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | (4-Chlorophenyl)(dimethoxyphosphiny l)methyl phosphoric acid dimethyl ester |
Solubility | Soluble to 100 mM in water |
Storage condition | Desiccate at RT |
References | Selective PPARγ antagonist; antidiabetic and antiobesity agent. Attenuates troglitazone-induced PPARγ transcriptional activity (IC50 = 140 μM) without affecting ligand-stimulated PPARα, PPARβ or FXR transcriptional activity. Inhibits PPARγ-dependent adipocyte differentiation and growth in vitro and in vivo. Improves insulin sensitivity in diabetic ob/ob mice and increases HDL levels in rats in vivo. Purity: >99 % |
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