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Cat. Number
SR 202
Chemical Name
SR 202
CAS Number
[76541-72-5]
Mol. Formula
C11H17ClO7P2
Mol. Weight
358.65
Qty 1
10mg
Qty 2
50mg
Synonym
(4-Chlorophenyl)(dimethoxyphosphiny l)methyl phosphoric acid dimethyl ester
Solubility
Soluble to 100 mM in water
Storage condition
Desiccate at RT
References
Selective PPARγ antagonist; antidiabetic and antiobesity agent. Attenuates troglitazone-induced PPARγ transcriptional activity (IC50 = 140 μM) without affecting ligand-stimulated PPARα, PPARβ or FXR transcriptional activity. Inhibits PPARγ-dependent adipocyte differentiation and growth in vitro and in vivo. Improves insulin sensitivity in diabetic ob/ob mice and increases HDL levels in rats in vivo.
Purity: >99 %
下一个:SR 2640 hydrochloride上一个:SR 142948
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