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| Cat. Number | SNS 032 |
| Chemical Name | SNS 032 |
| CAS Number | [345627-80-7] |
| Mol. Formula | C17H24N4O2S2 |
| Mol. Weight | 380.53 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | N-[5-[[[5-(1,1-Dimethylethyl)-2-oxa zolyl]methyl]thio]-2-thiazolyl]-4-piperidinecarbox amide |
| Solubility | Soluble to 50 mM in DMSO |
| Storage condition | Store at -20°C |
| References | Potent inhibitor of cyclin-dependent kinases (cdks) 9, 2 and 7 (IC50 values are 4, 38 and 62 nM respectively). Displays no activity against 190 additional kinases (IC50 >1000 nM). Arrests the cell cycle at G2/M; inhibits transcription, proliferation and colony formation, and induces apoptosis in RPMI-8226 multiple myeloma cells. Prevents tumor cell-induced VEGF secretion and in vitro angiogenesis. Purity: >99 % |
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