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| Cat. Number | SKF 89976A hydrochloride |
| Chemical Name | SKF 89976A hydrochloride |
| CAS Number | [85375-15-1] |
| Mol. Formula | C22H25NO2.HCl |
| Mol. Weight | 371.91 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 1-(4,4-Diphenyl-3-butenyl)-3-piperi dinecarboxylic acid hydrochloride |
| Solubility | Soluble to 100 mM in water and to 100 mM in DMSO |
| Storage condition | Desiccate at +4°C |
| References | A potent GABA uptake inhibitor, selective for GAT-1 (IC50 values are 0.13, 550, 944 and 7210 μM for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Inhibits transport current competitively (Ki = 7 μM) and transmitter-gated current non-competitively (Ki = 0.03 nM). Able to pass the blood-brain barrier after systemic administration and is active in vivo. Purity: >99 % |
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