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| Cat. Number | SKF 86002 dihydrochloride |
| Chemical Name | SKF 86002 dihydrochloride |
| CAS Number | [72873-74-6] |
| Mol. Formula | C16H12FN3S.2HCl |
| Mol. Weight | 370.27 |
| Qty 1 |
10mg |
| Qty 2 | 50mg |
| Synonym | 6-(4-Fluorophenyl)-2,3-dihydro-5-(4 -pyridinyl)imidazo[2,1-b]thiazole dihydrochloride |
| Solubility | Soluble to 50 mM in water |
| Storage condition | Desiccate at +4°C |
| References | Inhibitor of p38 MAP kinase (IC50 = 0.1 - 1 μM). Potently inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50 = 1 μM). Also inhibits 5-lipoxygenase- and cyclooxygenase-mediated arachidonic acid metabolism in RBL-1 cells (IC50 values are 10 and 100 μM respectively). Anti-inflammatory following oral administration in vivo. Purity: >98 % |
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