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/ Products Classification 点击展开+Cat. Number | SKF 83822 hydrobromide |
Chemical Name | SKF 83822 hydrobromide |
CAS Number | [74115-08-5] |
Mol. Formula | C20H22ClNO2.HBr |
Mol. Weight | 424.76 |
Qty 1 |
10mg |
Qty 2 | 50mg |
Synonym | 6-Chloro-2,3,4,5-tetrahydro-1-(3-me thylphenyl)-3-(2-propenyl)-1H-3-benzazepine-7,8-di ol hydrobromide |
Solubility | Soluble to 10 mM in ethanol and to 100 mM in DMSO |
Storage condition | Store at RT |
References | High affinity, selective dopamine D1-like receptor agonist. Ki values are 3.2, 3.1, 186, 66, 335, 1167, 1251 and 1385 nM at recombinant D1, D5, D2, D3, D4, 5-HT2A, α1A and α1B receptors respectively. Stimulates adenylyl cyclase (EC50 = 65 nM) but not phosphoinositide hydrolysis. Induces extreme arousal and hyperlocomotion following subcutaneous administration in monkeys. Purity: >98 % |